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Ebola pioneer, stem cell researcher honoured with Canada Gairdner Awards

CANADIAN PRESS                                                                                March 25, 2015
One of the co-discoverers of the Ebola virus and a leading Canadian stem cell researcher are among this year's winners of the prestigious Canada Gairdner Awards.

Dr. Peter Piot is the recipient of the Canada Gairdner Global Health Award, recognizing his work on the discovery of the Ebola virus in 1976 and his leadership in the global response to the HIV-AIDS epidemic.

Dr. Janet Rossant, chief of research at Toronto's Hospital for Sick Children, is the recipient of the 2015 Canada Gairdner Wightman Award, which honours a Canadian who has demonstrated outstanding leadership in medicine and medical science.

Five international scientists are also being honoured with Canada Gairdner Awards, two each from the United States and Japan and one from Switzerland....

Dr. Peter Piot won the 2015 Canada Gairdner Global Health Award in recognition of his work on the discovery of the Ebola virus in 1976 and his leadership in the global response to the HIV-AIDS epidemic. (David Azia/Associated Press)

Red complete story.

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Ebola virus not mutating as quickly as thought

SCIENCE NEWS  by Ashley Yaeger                                                      March 26, 2015

(Scroll down for full study.)

The virus causing the current Ebola epidemic in West Africa is not evolving as quickly as some scientists had suggested.

REGULAR RATE  A genetic analysis suggests that the Ebola virus, shown here in orange, is not evolving as fast as expected.

In a paper last August, researchers reported that the virus (Zaire ebolavirus) was altering its genes almost twice as fast as it had during previous Ebola outbreaks in Central Africa (SN: 9/20/14, p. 7). However, a new genetic analysis shows that the virus is mutating at roughly the same rate as in past outbreaks, researchers report online March 26 in Science. The finding suggests the virus has not become more virulent or transmissible during the West Africa outbreak.

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Ebola upsurge could undo progress in blink of an eye, warns expert

THE GUARDIAN by Sam Jones                           March 26, 2015

Despite the massive push to bring the number of new Ebola cases down to zero as quickly as possible, there will inevitably be “flare-ups” that could reverse the overall downward trend and prove difficult to contain, the UN’s response co-ordinator has warned.

Dr David Nabarro, the UN’s special envoy for Ebola, said the huge medical, administrative and logistical operation to fight the disease could still be set back by individuals ignoring official advice.

“There will be flare-ups, there will be disappointments; there will be people who evade quarantine – because nobody likes being told to stay put – there will be people who choose not to declare that they’ve got a relative ill, there will be people who get ill and just misdiagnose themselves,” he said....

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Strengthening the Detection of and Early Response to Public Health Emergencies: Lessons learned from, the Ebola outbreake

PLOS MEDICINE by Mark J. Siedner, Lawrence O. Gostin, Hilarie H. Cranmer,and John D. Kraemer                        March 24, 2015

In-depth paper on lessons learned from the West Africa Ebola outbreak

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Pandemic Disease: Never again

As the Ebola epidemic draws gradually to its close, how should the world arm itself against the risks of insurgent infections?

 THE ECONOMIST                                                                                        March 21,  2015

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Deconstructing “Malaria”: West Africa as the Next Front for Dengue Fever Surveillance and Control

sciencedirect.com - June 2014
Justin Stoler, Rawan al Dashti, Francis Anto, Julius N. Fobil, Gordon A. Awandare
doi:10.1016/j.actatropica.2014.02.017

CLICK HERE - Deconstructing “Malaria”: West Africa as the Next Front for Dengue Fever Surveillance and Control

Highlights

• Febrile illnesses are vastly overdiagnosed as malaria in many African settings.
• West Africa is emerging as a new front for dengue fever surveillance and control.
• Efficient health care utilization depends upon proper diagnosis of febrile illness.

Abstract

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Slow International Response to Ebola Epidemic Cost Thousands of Lives: MSF

TIME MAGAZINE  by Helen Regan                                March 23, 2015
(Scroll down for link to full MSF report.)

Paris-based Doctors Without Borders (MSF) has slammedthe international community’s slow response to the Ebola outbreak in West Africa, saying it cost thousands of lives that could otherwise have been saved.

A Doctors Without Borders (MSF), health worker in protective clothing carries a child suspected of having Ebola in the MSF treatment center on October 5, 2014 in Paynesville, Liberia.

The leading international medical charity released a report Monday coinciding with the one-year anniversary of the outbreak’s start. It said warnings that the disease’s spread was out of control were dismissed as alarmist and that early calls for help were ignored by local governments and the World Health Organization (WHO), reports Reuters.

“For the Ebola outbreak to spiral this far out of control required many institutions to fail. And they did, with tragic and avoidable consequences,” said MSF’s general director Christopher Stokes in the report.

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One Year Later, Ebola Outbreak Offers Lessons for Next Epidemic

IN DEPTH OVERVIEW OF THE EBOLA CRISIS AND LESSONS FOR THE FUTURE
NEW YORK TIMES  by Sheri Fink, MD,   and Pam Belluck                                     March 23, 2015

One year has passed since the declaration of what became the largest Ebola outbreak in history, with more than 10,000 deaths..

Assessing the lessons of an Ebola outbreak that became the largest in history, with 10,000 dead. Credit Daniel Berehulak for The New York Times

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Liberians overcome fear to volunteer for Ebola vaccine trial

ASSOCIATED PRESS  by Jpnathan Paye-Layleh             March 22, 2015

MONROVIA, Liberia — Liberians are overcoming their fears of Ebola to volunteer for a vaccine trial...

One year after the World Health Organization declared the Ebola outbreak, vaccine trials are under way in Liberia and Guinea. Sierra Leone will start a trial later this month.

In Liberia, scientists have fanned out across the country to explain the studies and reduce the fear and confusion that have stymied efforts to contain Ebola.

Dr. Stephen Kennedy, the Liberian lead investigator for the study, was among the first people to volunteer for the vaccine trial, getting his injection in front of the media. Similarly, in Guinea, authorities started the study by injecting a series of prominent officials, including the head of the country's Ebola response.

The outreach worked in Liberia, where more than 700 people have volunteered, well beyond the 600 required, according to Kennedy.

Read complete story.
http://news.yahoo.com/liberians-overcome-fear-volunteer-ebola-vaccine-trial-120848405.html

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How to stop the next epidemic

THE ECONOMIST                                                                                    May 19, 2015

..when the next epidemic breaks out, how do we prevent it from spreading around the world? It is easier said than done.
 
First: Early detection is critical, and it relies on good surveillance. But only 64 of the 194 member states of the World Health Organisation (WHO) have the surveillance procedures, laboratories and data-management capabilities required by the International Health Regulations. Improvements in things like basic public health infrastructure are needed...

Second: A swift response to an outbreak – which might involve getting skilled people, equipment and money to the right places – can potentially save more lives than drugs and vaccines. ... The World Health Organisation and the global community were slow to recognise that there was an international public health emergency.

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