Three years after the novel coronavirus emerged, a new variant, XBB.1.5, is quickly becoming the dominant strain in parts of the United States because of a potent mix of mutations that makes it easier to spread broadly, including among those who have been previously infected or vaccinated.
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Analysis: New variant XBB.1.5 is ‘most transmissible’ yet, could fuel covid wave
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Analysis: New variant XBB.1.5 is ‘most transmissible’ yet, could fuel covid wave
Mon, 2023-01-09 17:10 — mike kraftMore than 70 percent of cases in the Northeast are believed to be XBB.1.5.
While there is no evidence so far that XBB.1.5 is more virulent than its predecessors, a recent swirl of misinformation linking the rise of new variants to vaccination has cast a spotlight on this latest strain and raised concern among some health experts that it could further limit booster uptake.
“XBB did not evolve because people were vaccinated,” said Vaughn Cooper, a professor of evolutionary biology at the University of Pittsburgh. “The way it evolved, let’s be straight, is because people were infected by multiple viruses at the same time.”
Since the omicron variant ignited an explosion of cases last winter, it spawned a host of descendants that are even more adept at slipping past antibodies and caused most infections in the United States. The XBB line emerged as a result of two other omicron subvariants swapping parts.
Virologists who studied XBB.1.5 say it does not appear better at escaping antibodies than other immune-evading predecessors, but it is better at binding to the cell and replicating. That means it can more easily become the dominant strain in a community than its relatives, but it doesn’t necessarily worsen an individual’s covid symptoms.
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