Situation Report

Morbidity and Mortality Weekly Report (MMWR)

CDC                                                                                                                            Feb. 13, 2015

by Cheri Grigg, DVM1,2, Ndadilnasiya E. Waziri, DVM3, Adebola T. Olayinka, MD3, John F. Vertefeuille, PhD4

On July 20, 2014, the first known case of Ebola virus disease (Ebola) in Nigeria, in a traveler from Liberia  led to an outbreak that was successfully curtailed with infection control, contact tracing, isolation, and quarantine measures coordinated through an incident management system.

During this outbreak, most contacts underwent home monitoring, which included instructions to stay home or to avoid crowded areas if staying home was not possible. However, for five contacts with high-risk exposures, group quarantine in an observation unit was preferred because the five had crowded home environments or occupations that could have resulted in a large number of community exposures if they developed Ebola.

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http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6405a3.htm?s_cid=mm6405a3_x

THE LANCET  by  Anna  Petherick  Volume 385, No. 9968, p591–592, 14 February 2015
The (West Africa) region has presented unforeseen challenges, and the three worst affected countries have put in place different response strategies. Anna Petherick reviews some of the lessons learned so far.

The early history of the ongoing Ebola outbreak in west Africa is a salutary statement about the lack of infectious disease surveillance capacity in one of the world's poorest regions....

Opportunities to contain the virus were lost soon after, largely because of a lack of trust between local communities and the officials and medical professionals trying to nip the epidemic in the bud.

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http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2815%2960075-7/fulltext

CDC EID JOURNAL by  Lisa E. Hensley, Julie Dyall, Gene G. Olinger, and Peter B. Jahrlin (NIH)                     Feb. 12, 2015

The unprecedented number of Ebola virus disease (EVD) cases in western Africa has compelled the world to consider experimental and off-label therapeutics to mitigate the current outbreak. For clinicians, approved drugs are an attractive solution because of known safety profiles and availability.

Oral lamivudine (GlaxoSmithKline, Brentford, UK), a US Food and Drug Administration–approved anti-HIV drug, has been suggested as a possible antiviral agent against Ebola virus (EBOV). In September 2014, a Liberian physician, Dr. Gorbee Logan, reported positive results while treating EVD with lamivudine (1). Thirteen of 15 patients treated with lamivudine survived presumed EVD and were declared virus free. Clinical confirmation of EVD in these cases remains to be verified....

REUTERS   by  Katie Nguyen                                                                                       Feb. 11, 2015

LONDON - Britain's decision to stop direct flights to Ebola-hit countries had "no scientific justification", probably increased the cost of dealing with the outbreak and should be reversed, a parliamentary watchdog said on Wednesday.

Several airlines including British Airways and Emirates stopped flights last year to countries in West Africa affected by the worst outbreak of Ebola since the deadly virus was identified in 1976.

In September, independent health advisers to the World Health Organization (WHO) concluded that there should be no general ban on travel or trade with Ebola-affected areas....

The committee also criticized the Department for International Development (DFID) for failing to respond to the crisis with enough urgency. It said DFID should focus on strengthening healthcare systems in the region so they could cope better with future public health emergencies.
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http://news.yahoo.com/uk-resume-flights-ebola-hit-nations-parliamentary-watchdog-132034795--finance.html;_ylt=AwrBEiHpi9tUnhAA7srQtDMD