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" 10 drugs that could stop Ebola "

FIERCE BOIOTECH RESEARCH                       Oct. 14, 2014
By Emily Mullin

Before the current Ebola outbreak, the virus had only appeared in Africa in fits and starts since its discovery in 1976, receding back into the jungle almost as quickly as it arrived. This relative rarity and the swiftness with which the disease kills its victims has, up until now, made Ebola an unattractive--not to mention daunting--prospect for drug developers. As a result, no approved drugs or vaccines against Ebola exist.

...the current situation in West Africa... has prompted the World Health Organization to call on international government agencies and the pharmaceutical industry to work together to speed up the development of promising therapies for experimental use for those most at risk of contracting the disease, which causes severe hemorrhagic fever.

Now, a handful of players are racing to get a treatment or vaccine to patients as quickly as possible, even though these drugs remain largely untested in humans.... 

Here is a list of organizations that are in the global spotlight right now with their investigational Ebola program

See full story and list

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WHO: Ebola spreading in W. Africa, threatens Ivory Coast; some areas see fewer cases

THE WASHINGTON POST
By Joel Achenbach                                                  October 14 at 9:15 AM

The World Health Organization issued a mixed report Tuesday on progress in the fight against the Ebola epidemic in West Africa, noting that the number of new cases is dropping in some areas that had been hit hard by the virus earlier this year. But the disease is spreading across a broader geographical region, including along the Ivory Coast border, and continues to be rampant in some capital cities.

Ebola is killing 70 percent of the people who become infected, said Bruce Aylward, WHO assistant director-general overseeing the organization’s response to the West Africa epidemic. In a conference call with journalists, he said the official statistics do not capture the true lethality of the virus.

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Ebola outbreak threatens peace, security, WHO chief says

GENEVA — The Ebola outbreak in West Africa is “unquestionably the most severe acute public health emergency in modern times,” Dr. Margaret Chan, the director general of the World Health Organization, said Monday.

Chan, who dealt with the 2009 avian flu pandemic and the SARS outbreaks of 2002-03, said the Ebola outbreak had progressed from a public health crisis to “a crisis for international peace and security.”

“I have never seen a health event threaten the very survival of societies and governments in already very poor countries,” she said in a statement delivered on her behalf to a conference in Manila, Philippines, and released by her office in Geneva. “I have never seen an infectious disease contribute so strongly to potential state failure.”

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WHO and Partners agree on a common approach to strengthen Ebola preparedness in unaffected countries

Brazzaville, 10 October 2014 - The World Health Organization (WHO) and partner organizations meeting in Brazzaville have agreed on a range of core actions to support countries unaffected by Ebola in strengthening their preparedness in the event of an outbreak.

Building on national and international existing preparedness efforts, a set of tools is being developed to help any country to intensify and accelerate their readiness.

One of these tools is a comprehensive checklist of core principles, standards, capacities and practices, which all countries should have or meet. The checklist can be used by countries to assess their level of preparedness, guide their efforts to strengthen themselves and to request assistance. Items on the checklist include infection prevention control, contact tracing, case management, surveillance, laboratory capacity, safe burial, public awareness and community engagement and national legislation and regulation to support country readiness.

“While we rightly focus on stopping the outbreak in affected countries, we should not forget that all other countries are at risk, albeit at varying levels”, said WHO Regional Director for Africa, Dr Luis Sambo.

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Tweets About Ebola - NowTrending.HHS.gov

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FIVE ITEMS ON EFFORTS TO IMPROVE TRAINING FOR HEALTH WORKERS

Scroll down for the stories and link to CDC check list

CDC TAKES NEW STEPS TO IMPROVE TRAINING FOR HOSPITAL WORKERS

NEW YORK TIMES                   Oct. 13, 2014
By Pam Belluck

The Centers for Disease Control and Prevention is taking new steps to help hospital workers protect themselves, providing more training and urging hospitals to run drills to practice dealing with potential Ebola patients.

In response to the news that a health care worker in Dallas had contracted Ebola, a spokeswoman said the agency would also issue more specific instructions and explanations for putting on and removing protective equipment and would urge nurses and doctors to enlist a co-worker or “buddy” to watch them do so....

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Ebola outbreak: Liberia health workers threaten to strike Monday

UPDATE  Liberia largely averts health worker strike that would have severely hampered Ebola response

ASSOCIATED PRESS            Updated: October 13, 2014 - 11:45 AM

By: JONATHAN PAYE-LAYLEH , Associated Press

MONROVIA, Liberia — Health workers reported for duty at Liberia's hospitals on Monday, largely defying calls for a strike that could have further hampered the country's ability to respond to the worst Ebola outbreak in history.

Nurses and other health workers — though not doctors — had threatened to strike if they did not receive the higher hazard pay they had been promised by the government. That would have made the already difficult care of Ebola patients even harder, since the bulk of the staff at clinics and hospitals is made of up of Liberia's nurses, physician assistants and community health workers.

"Considering the situation in which we find ourselves we don't think strike is the way forward," said Dr. Jerry Brown, head of ELWA2, a treatment center on the outskirts of Monrovia. "Because if we strike now, more and more patients will remain in the communities. And as more and more patients remain in the communities, there will be more new cases and there will be a setback."

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Working with Communities is the Key to Stopping Ebola

who.int - October 2014

When Dr Peter Clements arrived in Lofa County, Liberia eight weeks ago, from the WHO country office in Monrovia, 20-30 patients were arriving at the MSF hospital with Ebola-like symptoms every day. People living in the community were afraid, civil unrest was simmering, and an ambulance and health workers were being targeted

Although UN security advised him not to, Dr Clements traveled the 12 hours over dirt roads to the area nearest the Guinea border. Once there, he walked into the hostile communities and went straight to the chiefs.

“In many years, you have not fought with these people,” he said. “Now you attack them. They are not the enemy, Ebola is the enemy. If we don’t chase Ebola, it will kill us. You have to know Ebola to fight Ebola. Mobilize your people. Let’s get to know Ebola.”

Dr Clements said the key to working with a hostile community is listening first. So he patiently listened to the community to understand their fears, then he started to explain about the virus and how people become sick, and people can prevent themselves.

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Obama orders CDC probe in 2nd Dallas Ebola case to move ‘as expeditiously as possible’

WASHINGTON POST

                                    October 12, 014 

President Obama received two briefings on the diagnosis of a second Ebola case in Dallas, according to White House officials, and Sen. John McCain (R-Ariz.) urged the president to appoint a "czar" to coordinate the administration's response to the disease.

Obama was briefed Sunday morning by Lisa Monaco, who serves as assistant to the president for homeland security and counterterrorism and is overseeing the interagency response to the disease. Later, according to White House officials, Obama also discussed the situation with Health and Human Services Secretary Sylvia Burwell.

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Liberia already had only a few dozen of its own doctors. Then came Ebola.

Detailed description of the impact of Ebola on Liberian health workers

THE WASHINGTON POST                            Oct. 12, 2014

By Kevin Sieff October 11 at 11:11 PM

MONROVIA, Liberia — They were among the only Liberians who could treat Ebola, and in a single morning, it felt as if they were being picked off one by one.

First, before dawn on Thursday, Ebola killed Dr. John Tata. Then, hours later, Dr. Thomas Scotland tested positive for the virus.

With only a few dozen Liberian physicians in a country facing the biggest Ebola outbreak in history, it was a crippling blow. One Ebola treatment center closed its doors. Several of its hygienists and clinicians quit. Others left their shifts early to weep quietly outside.

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