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What ‘100 Percent Effective’ Means for That Ebola Vaccine

Analysis
WIRED.COM by Katie M. Palmer                                                            Aug. 4, 2015

Last week, the medical journal the Lancet published preliminary results on the efficacy of an Ebola vaccine in Guinea, and everybody got really excited—especially about one particular figure. The vaccine, the results suggested, was 100 percent effective at protecting against Ebola, a thrilling prospect in the face of an epidemic that has killed more than 11,000 people. ...

But that number probably means less than you think it does. It’s based on incomplete data, so it doesn’t have the statistical clout it should. And it never will. Based on the vaccine’s early success, the trial’s runners decided that all participants in the study should get it immediately after exposure. That’s a perfectly reasonable, humane reaction, but it also means that the researchers will never be able to collect better data on the vaccine’s efficacy, which is what regulators look for when they’re deciding to approve a drug. In other words, the vaccine’s early success could make it harder for people to get it down the line.

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Arktek Passive Vaccine Storage Device - P6

      

From watching the video in the link below, the Arktek vaccine cold storage device is also known as the P6 . . .
http://www.intellectualventures.com/inventions-patents/our-inventions/vaccine-cold-chain-device/

The P6 is not just a container, but an innovative high-tech device.  It is designed to keep vaccines at the appropriate temperatures for a month or more with repeat vaccine retrievals and no need for electricity (using just one initial batch of ice).  The device also has built-in communications and monitoring capability.  The P6 units are able to send live updates, including the units’ GPS positions viewable on interactive maps, the number of days since fresh ice had been added, temperature, and more.  Here are the details . . .
http://www.intellectualventureslab.com/invent/a-story-of-invention-the-passive-vaccine-storage-device

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WHITE HOUSE FACT SHEET: The Global Health Security Agenda

The U.S. Government announces it intends to invest more than $1 billion in resources to expand the Global Health Security Agenda to prevent, detect, and respond to future infectious disease outbreaks overseas.

THE WHITE HOUSE PRESS OFFICE                       July 28, 2015

The Ebola epidemic in West Africa continues to galvanize global attention and resources as the international community strives to eliminate active cases and help the affected countries recover.  African leaders and African Union officials have shown extraordinary leadership in addressing the outbreak. The epidemic highlighted the urgent need to establish global capacity to prevent, detect, and respond to biological threats – to prevent future outbreaks from becoming epidemics. 

Beginning with the release of the National Strategy for Countering Biological Threats in 2009, and outlined in his 2011 speech at the United Nations General Assembly, President Obama has called upon all countries to come together to prevent, detect, and respond to infectious disease threats, whether naturally occurring, accidental or deliberately spread.  Today, the President underscored the unwavering U.S. commitment to partnering with Africans, their governments, and all who will join the effort to improve health security across the continent and for all people.

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How West Africa is ramping up food security after Ebola outbreak

Countries in West Africa and the international community are teaming up to fight Ebola's  lingering effects on food security and agriculture.

Volunteers distribute food at a World Food Programme storage center in Monrovia October 16, 2014. Almost a year after the Ebola outbreak garnered strength in West Africa, countries in that region and the international community are teaming up to fight the disease's lingering effects on food security and agriculture. James Giahyue/Reuters/File

CHRISTIAN SCIENCE MONITOR by Clare Algozin                                    July 29, 2015

As the death toll of EVD rose, West African countries began to experience labor shortages, and many fields of crops went unharvested, according to U.N. Food and Agriculture Organization (FAO). As part of the measures to prevent the spread of EVD, many West African governments established quarantine zones and restricted the movements of people.

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FAO - Manual on Livestock Disease Surveillance and Information Systems

fao.org

Introduction

The FAO has always been concerned with agricultural development and food security. Recent disease epidemics, in both developing and industrialised countries, have once again focussed attention on livestock disease and their potential to harm development. In the context of developing countries, disease epidemics do four things:

They reduce herds and flocks dramatically, which, in the case of pastoral peoples, is a major blow to food security and the ability to survive;

They cause trading partners to - quite understandably - put trade barriers in place in order to protect their own countries from infection. Where livestock or meat exporting countries are affected by epidemics, their "pariah" status can cost millions of dollars in terms of foreign exchange losses, and drive farmers and the local meat industry to the wall.

They are a deterrent to sustained livestock production.

They add significantly to the cost of livestock production through the necessity for the application of costly disease control measures.

(CLICK ON THE LINKS BELOW - FAO - Manual on Livestock Disease Surveillance and Information Systems)

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Ebola created a public health emergency—and we weren’t ready for it

Could the international community have done a better job when confronted with the outbreak of Ebola in West Africa? Although the virus appears to be largely contained now, this comes after at least 27,000 people were infected, with 11,000 of them dying. The virus also had the opportunity to spread within the human population for over a year, providing it a potentially dangerous opportunity to adapt to us as hosts.

To find out whether we could have managed the outbreak better, the World Health Organization (WHO) recently convened an Ebola Interim Assessment Panel, which analyzed various aspects of the organization’s response. This panel, commissioned by the WHO Director-General, included the Dean of the Harvard School of Public Health, the founding Director of the UK's national Health Service, and other international public health leaders. It recently released its final report on the crisis.

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Bird Flu Spreading Across West Africa, Human Spillover Feared: UN

          

A man poses with a chicken at a local market in Gombe state, Nigeria, January 30, 2015. REUTERS/ Afolabi Sotunde

trust.org - Thomson Reuters Foundation - by Chris Arsenault - 20 Jul 2015

A highly contagious strain of avian flu is spreading across West Africa, decimating poultry farms and stoking fears the virus will jump from birds to humans, the U.N.'s food agency warned on Monday.

Markets and farms in Nigeria, Burkina Faso, Niger, Ivory Coast and Ghana have been hit with the deadly H5N1 virus over the past six months, the U.N.'s Food and Agriculture Organization (FAO) said.

If the virus continues to spread, it could affect more than 330 million people across West Africa, hurting food security and human health in a region still recovering from the Ebola crisis.

"Urgent action is needed to strengthen veterinary investigation and reporting systems... to tackle the disease at the root, before there is a spillover to humans," Juan Lubroth, head of the FAO's animal health division, said in a statement.

(READ COMPLETE ARTICLE)

(ALSO SEE RELATED ARTICLES IN THE LINKS BELOW)

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RECORDED VIDEO - Ebola Innovation for Impact 2015 - Game Change in Global Health Crisis Management

Side Event in Support of the UN Secretary-General’s International Ebola Recovery Conference July 9-10 2015

United Nations Headquarters - Conference Room 3, 13.15-14.30 pm (1:15pm-2:30pm, ET), 10 July 2015

As a side-event in support of the United Nations Secretary-General’s International Ebola Recovery Conference, Ebola Innovation for Impact 2015: Game Change in Global Health Crisis Management will bring together thought leaders in global health and technology to stimulate creative, collaborative and catalytic action, and to address the Ebola crisis with innovative solutions in the key, inter-linked areas of: Community Engagement and Mobilization; Private Sector Contribution and Collaboration; Data Systems Strengthening and Coordination; and, Emergency Infrastructure and Logistics.

Speakers include:

Dr. Barbara Bentein, UNICEF

Dr. Arnaud Bernaert, World Economic Forum (WEF)

Dr. Vinton G. Cerf, Google

Dr. Denis Gilhooly, Global Digital Health Initiative (GDHI)

Dr. Michael D. McDonald, Global Health Response & Resilience Alliance (GHRRA)

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International Ebola Recovery Conference, 9-10 July 2015

                                                            

ebolaresponse.un.org/recovery-conference

The road towards recovery

Guinea, Liberia and Sierra Leone have undertaken a remarkable effort to defeat the devastating Ebola outbreak. Thanks to those efforts and the support of the international community, the affected countries have seen a significant decline in the number of new cases. Recovery must now be pursued as part of the goal of “getting to zero and staying at zero,” as the response changes from emergency operations to multi-faceted, long-term support.

To this end, UN Secretary-General Ban Ki-moon is hosting an International Ebola Recovery Conference in New York to ensure that recovery efforts go beyond redressing direct development losses to build back better and ensure greater resilience.

The Conference will be held in cooperation with the Governments of Guinea, Liberia and Sierra Leone, and in partnership with the African Union, the African Development Bank, the European Union and the World Bank.

Aims of the Conference

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Ebola Innovation for Impact - 2015 Data Strengthening, Situational Awareness & Coordination Working Group Sessions

                                                                

1:00-5:00 pm, July 8, 2015

Manhattan Room, One UN Plaza, Second Floor

44th St. and 1st Ave., New York City

Agenda

On Wednesday July 8, 2015, an afternoon session will address Ebola response & recovery data strengthening, situational awareness, and coordination.  This working session will be held at U.N. headquarters in New York or a facility nearby from 1:00 PM to 5:00 PM.

Following are the proposed elements of the July 8 afternoon session:

1:00 PM           40 mins                        Opening Plenary Session

            An Overview of West Africa’s Current & Emerging Infrastructures

                        Barbara Bentein           UNICEF

                        Juliet Benford               Anthrologica

                        Sara Glass                   USAID, Global Development Lab

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