Global

submitted by George Hurlburt

scicasts.com - November 2, 2015

CLICK HERE - STUDY - Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention - Ziying Han, Jonathan J. Madara et al. PLOS Pathogens (2015)

Philadelphia, PA (Scicasts) — The Ebola virus acts fast. The course of infection, from exposure to recovery, or death, can take as little as two weeks. That may not leave enough time for the immune system to mount an effective response.

The goal of some anti-viral therapies, therefore, is to buy more and give the immune system a leg up on the virus. A new study led by Bruce Freedman and Ronald Harty in the Department of Pathobiology of the University of Pennsylvania School of Veterinary Medicine demonstrates a way to do that, by reducing the ability of the virus to exit a host cell and spread. Their work showed that blocking a calcium-signalling pathway could inhibit not only the Ebola virus, but also Marburg, Lassa and Junin viruses, all sources of deadly infections.

submitted by George Hurlburt  

The new Sensi Technology Innovation Hub hopes to help the country rebuild after its Ebola crisis

cnn.com - by Peter Guest - November 7, 2015

(CNN) - Morris Marah was working in the Sierra Leonean High Commission in London when the devastating Ebola outbreak struck his country last year.

Desperate to help, he went home; first to volunteer in a community health center, then by applying his technology skills to build an SMS-based platform that disseminated weekly information and advice on how to avoid contracting the disease to more than 500,000 people.

"I felt, sitting in London there wasn't much I could do from that far away. I wanted desperately to come out here and see how I could be useful," he says over the phone from the capital, Freetown.

Working on that platform, called Sensi, and on other public health initiatives demonstrated how successfully technology could be leveraged for social good, and inspired him to look for ways to bring the country's small, but talented, tech community together to help restart the country's stalled economy.

(READ COMPLETE ARTICLE)

US NEWS AND WORLD REPORT HEALTHDAY NEWS by Robert Preidt,  Nov. 6, 2015

Ebola patients are more likely to survive if they are hospitalized soon after being infected, a new study finds.

Researchers analyzed data from nearly 1,000 cases of Ebola virus that occurred in the Democratic Republic of Congo over 38 years. They found that each day of delay in hospital admission was associated with an 11 percent higher risk of death during epidemics.

Delays in hospitalization were caused by factors such as geography, infrastructure and cultural influences, the researchers said.

The Democratic Republic of Congo has had more Ebola outbreaks than any other country since the deadly virus was discovered in 1976, they noted.

The researchers also found that rapidly progressing Ebola outbreaks are swiftly brought under control, while national and international responses to slower-progressing outbreaks tend to be less intense. As a result, those outbreaks last longer, the study authors said.

The study was published Nov. 3 in the journal eLife.

Read complete story.

http://health.usnews.com/health-news/articles/2015/11/06/each-1-day-delay-in-hospitalization-ups-risk-of-ebola-death

Thomson Reuters Foundation - trust.org - by SciDev.Net - Gilbert Nakweya - October 29, 2015

Floods, disease and crop losses expected in coming months

Kenya has built camps for displaced people and is ready for cholera

East African farmers may face drought after the rains

[NAIROBI] East African countries near the equator are bracing for high El Niño-related rainfall that meteorologists warn may cause floods, crop losses and disease in the coming months.   The region is set to experience much more rain than usual during the October-December wet season, and possibly until early next year, forecasts say — although the rains may be less heavy than those experienced during the powerful 1997-98 El Niño ocean warming event.   The World Meteorological Organization (WMO), Kenya Meteorological Department, Tanzania Meteorological Agency and Uganda National Meteorological Authority have issued warnings about the risks associated with higher rainfall.   The Famine Early Warning Systems Network says flooding along rivers and lakes, such as Lake Victoria, and flash floods in lowland areas of Ethiopia, Kenya, Somalia and Tanzania are likely to force people from their homes, lead to crop and livestock losses, and make it difficult for people to access food and work.