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Ebola outbreak: Virus still 'running ahead of us', says WHO

BBC    by Tulip Mazumdar                                                                                                    Dec. 10, 2014

The Ebola virus that has killed thousands in West Africa is still "running ahead" of efforts to contain it, the head of the World Health Organization has said.
Director general Margaret Chan said the situation had improved in some parts of the worst-affected countries, but she warned against complacency.

The risk to the world "is always there" while the outbreak continues, she said.

She said the WHO and the international community failed to act quickly enough....

"It is fair to say the whole world, including WHO, failed to see what was unfolding, what was going to happen in front of our eyes," said Dr Chan.

"Of course, with the benefit of hindsight, if you ask me now... we could have mounted a much more robust response."

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http://www.bbc.com/news/health-30400304

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Time Magazine Person of the Year: the Ebola fighters

 

TIME MAGAZINE    by Nancy Gibbs                                                                                                      Dec. 10, 2014

They risked and persisted, sacrificed and saved. Editor Nancy Gibbs explains why the Ebola Fighters are TIME's choice for Person of the Year 2014

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http://time.com/time-person-of-the-year-ebola-fighters-choice/

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Ebola Infections Fewer Than Predicted by Disease Models

A few months ago the U.S. Centers for Disease Control and Prevention predicted that up to 1.4 million people in Liberia and Sierra Leone could become infected with Ebola by mid-January. In a recent address to the Senate, CDC director Tom Frieden said that worst-case scenario would not pan out.

That is partly because health care workers in the Ebola hot zone are engaged in a battle to contain the epidemic. It is also because of assumptions about human and viral behavior that are built into the mathematical models used to predict the spread of infectious diseases. Assumptions are inherent in these models. “You take islands of data from different places and build bridges of assumptions that link up all these islands,” says Martin Meltzer, senior health economist at the CDC. Meltzer’s model, which predicted the 1.4 million infections in Liberia and Sierra Leone, worked on the assumption that things would not improve. “Our forecasts are based on the idea that nothing will change,” he says.

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Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

wwwnc.cdc.gov/eid

Schoepp RJ, Rossi CA, Khan SH, Goba A, Fair JN. Undiagnosed acute viral febrile illnesses, Sierra Leone. Emerg Infect Dis [Internet]. 2014 Jul [date cited]. http://dx.doi.org/10.3201/eid2007.131265

DOI: 10.3201/eid2007.131265

CLICK HERE - RESEARCH - Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

Table of Contents – Volume 20, Number 7—July 2014

Abstract

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VIDEO - Council on Foreign Relations - Ebola Update: Assessment From Africa

Archived Video - Watch the meeting held on Tuesday, December 9, 2014, from 1:00 to 2:00 p.m. (ET).

Speakers: Nancy A. Aossey, President and Chief Executive Officer, International Medical Corps

Laurie Garrett, Senior Fellow for Global Health, Council on Foreign Relations; Author, Ebola: Story of an Outbreak

David Nabarro, Special Envoy on Ebola, United Nations

Presider: Richard E. Besser, Chief Health and Medical Editor, ABC News

Experts recently returned from trips to West Africa with medical teams operating Ebola-treatment units there discuss the situation on the ground and developments in the international response to the crisis.

CLICK HERE - Council on Foreign Relations - Ebola Update: Assessment From Africa

CLICK HERE - YouTube - Council on Foreign Relations - Ebola Update: Assessment From Africa

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Surviving Ebola

      

Decontee Davis: She won her battle with Ebola. Her 5-year-old son, though, paid a price. She didn’t want other kids to suffer the same way, so she embarked on a difficult new job.

washingtonpost.com

Decontee Davis, 23, works at a child-care center, where any of the 13 children could be coming down with Ebola.  All are from homes where parents or guardians have been taken away to treatment centers or died of Ebola, and now the youngsters must be monitored for 21 days to determine whether they are infected as well.

The job falls to a staff of 10, all survivors of Ebola like Davis, who watch them 24 hours a day.

(READ COMPLETE ARTICLE)

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Rapid Ebola test is focus of NIH grant to Rutgers scientist

REPORTS Of RESEARCH ON TWO METHODS OF RAPID TESTING FOR EBOLA

(Two items, scroll down)

MEDICAL PRESS                                                                                     Dec. 8, 2014

Rutgers researcher David Alland, working with the California biotechnology company Cepheid, has received a grant of nearly $640,000 from the National Institutes of Health to develop a rapid test to diagnose Ebola as well as other viruses that can cause symptoms similar to Ebola.

Researchers will adapt this cartridge, now used worldwide for tuberculosis screenings, to collect and test samples from potential Ebola patients. Credit: John Emerson

Alland, a professor of medicine and associate dean for clinical research at Rutgers New Jersey Medical School and the principal investigator of the project, says would be able to take the test to small villages and other remote locations where the spread of Ebola has been especially rampant and diagnose patients where they live...

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In Ebola Outbreak, Bad Data Adds Another Problem

ASSOCIATED PRESS -By MARIA CHENG and SARAH DiLORENZO Dec. 14, 2014

LONDON--As health officials struggle to contain the world's biggest-ever Ebola outbreak, their efforts are being complicated by another problem: bad data.

Having accurate numbers about an outbreak is essential not only to provide a realistic picture of the epidemic, but to determine effective control strategies. Dr. Bruce Aylward, who is leading the World Health Organization's Ebola response, said it's crucial to track every single Ebola patient in West Africa to stop the outbreak and that serious gaps remain in their data.

"As we move into the stage of hunting down the virus instead of just slowing the exponential growth, having good data is going to be at the heart of this," Aylward said. "We are not there yet and this is something we definitely need to fix."

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Ebola in Graphics: The toll of a tragedy

THE ECONOMIST                                                                                                      Dec. 4, 2014

THE first reported case in the Ebola outbreak ravaging west Africa dates back to December 2013, in Guéckédou, a forested area of Guinea near the border with Liberia and Sierra Leone. Travellers took it across the border: by late March, Liberia had reported eight suspected cases and Sierra Leone six. By the end of June 759 people had been infected and 467 people had died from the disease, making this the worst ever Ebola outbreak. The numbers keep climbing. As of November 30th, 17,145 cases and 6,070 deaths had been reported worldwide, the vast majority of them in these same three countries. Many suspect these estimates are badly undercooked.

Read complete posting
http://www.economist.com/blogs/graphicdetail/2014/12/ebola-graphics

Link to an interactive map of the virus's current global reach:

http://www.economist.com/blogs/graphicdetail/2014/12/interactive-ebola-map

 

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Doctors Try Survivors’ Blood to Treat Ebola

Clinical Trials Are Being Launched in Africa but Face Challenges in Designing Ethical Studies, Compensating Donors

WALL STREET JOURNAL                                                                                                    Dec. 5, 2014
by Betsy McKay in Atlanta, David Gauthier-Villars in Conakry, Guinea, and Patrick McGroarty in Monrovia, Liberia

...Nearly a year after Ebola began spreading in West Africa, and with a proven drug or vaccine still far off, researchers are launching clinical trials on a product at hand: the blood of survivors.

 They want to determine whether so-called convalescent plasma or serum, chock full of antibodies, can help fight off the disease. But they face a number of complexities in carrying out the trials, including persuading survivors to participate....

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