Situation Report

New research suggests that Ebola's deadly inflammatory effects may be caused by the result of protein shedding by infected cells. (Victor Volchkov / PLOS Pathogens)

CLICK HERE - RESEARCH - PLOS Pathogens - Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability

latimes.com - by Monte Morin - November 20, 2014

New research suggests that the massive and destructive inflammation that characterizes Ebola virus disease may be caused by the release of foreign proteins from infected cells.

Although Ebola is infamous for causing bleeding in some of its victims, doctors say the vast majority of deaths are the result of organ failure and shock brought on by the uncontrolled release of cytokines, compounds that cells use to communicate with one another and control immune response. . .

. . . In a paper published Thursday in Plos Pathogens, researchers at the Claude Bernard University of Lyon, in France, argued that glycoprotein shedding by infected cells may explain the immune system's damaging response.

WALL STREET JOURNAL                                                                                               Nov. 21, 2014

By Andrew Morse

ZURICH—Nearly 5,500 people have died from Ebola, the World Health Organization said Friday, adding that the rate of transmission remains intense in the three West African countries at the center of the epidemic.

Medical staff members of the Croix Rouge NGO put on protective suits before collecting the corpse of a victim of Ebola, in Monrovia, Liberia. Agence France-Presse/Getty Images

In an update, the United Nations health agency said 15,351 confirmed, suspected or probable cases of Ebola had been reported in eight countries that have been affected by the disease. Most of the cases were concentrated in Guinea, Liberia and Sierra Leone.

A total of 5,459 people have died of Ebola since the outbreak began, the WHO said. On Wednesday, the WHO reported 15,145 cases and 5,420 deaths.

Ebola’s true overall toll is difficult to gauge because some hard-hit villages are remote and urban centers have showed resistance toward clinics....

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REUTERS                                                                                                                      Nov. 20, 2014
By Julia Edwards

WASHINGTON-- The Department of Homeland Security will grant temporary protected status to people from the three West African countries most affected by Ebola who are currently residing in the United States, department officials said on Thursday.

People from Liberia, Guinea, and Sierra Leone in the United States as of Thursday may apply for protection from deportation, as well as for work permits, for 18 months, said a Department of Homeland Security official.

REUTERS                                                                                                                             nOV. 19, 2014         
By Joe Brock
JOHANNESBURG (Reuters) - The cost of the Ebola epidemic for Sub-Saharan Africa's economy is likely to be closer to $3 billion-$4 billion and not the worst-case scenario of $32 billion, the World Bank's chief economist for the continent said on Wednesday.

Francisco Ferreira said at a lecture in Johannesburg that successful containment of Ebola in some West African countries made the gloomiest forecasts less likely, but the economic damage could still escalate if there was any complacency.

"The risk of the highest case of economic impact of Ebola has been reduced because of the success of containment in some countries. It has not gone to zero because a great level of preparedness and focus is still needed," Ferreira said.

"I would say the outlook has moved closer to the lower case of $3-$4 billion, than the upper case," he said.

In a report in October, the World Bank said that if the Ebola epidemic spread significantly outside the epicentre states of Guinea, Sierra Leone and Liberia, the potential cost for Africa in disrupted cross-border trade, supply chains and tourism could amount to tens of billions of dollars.