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New England researchers help shape the fight on Ebola

THE BOSTON GLOBE                                  Nov. 3, 2014

By Carolyn Y. Johnson

Northeastern University researchers use computers to simulate 20 million virtual Ebola outbreaks each week. Yale scientists are building three models that project the spread of the deadly disease. And a team at Boston Children’s Hospital is combing through data to gauge whether medical interventions are working.

....  they are providing a constant stream of evidence that is beginning to reveal the weak spots of the epidemic. For example, scientists’ models are beginning to identify basic patterns of who is being infected and when and how Ebola is being spread, which could help identify the most meaningful ways to intervene.

...According to their model, isolating three-quarters of the patients within the first four days that they show symptoms would help eliminate the disease.

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http://www.bostonglobe.com/metro/2014/11/02/ebola-disease-modelers-new-england-help-predict-future-spread-best-strategies/LZHSEGlInJs6SflLWW0yaP/story.html

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Nigerian-virologist-delivers-scathing-analysis-africas-response-ebola

SCIENCE INSIDER                                         Nov. 3, 2014

By Kai Kupferschmidt

VIENNA—After Oyewale Tomori finished his talk on Ebola here at the International Meeting on Emerging Diseases and Surveillance, there was stunned silence. Tomori, the president of the Nigerian Academy of Science, used his plenary to deliver a scathing critique of how African countries have handled the threat of Ebola and how corruption is hampering efforts to improve health. Aid money often simply disappears, Tomori charged, "and we are left underdeveloped, totally and completely unprepared to tackle emerging pathogens."

"Ebola is Africa's problem," says Oyewale Tomori.

 

Trained as a veterinarian, Tomori was the World Health Organization’s (WHO's) regional virologist for the African region in 1995 during the Ebola outbreak in Kikwit in the Democratic Republic of the Congo (DRC).

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Home> Health 'Post-Ebola Syndrome' Persists After Virus Is Cured, Doctor Says

ABC NEWS                                       Nov. 3, 2014
By via Good Morning America

West Africans fortunate to survive Ebola may go on to develop what's being called "post-Ebola syndrome," characterized by vision loss and long-term poor health, a doctor told a World health Organization.

People stand in the "red zone" where they are being treated for Ebola at the Bong County Ebola Treatment Unit in Monrovia, Liberia, Oct. 28, 2014.

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Ebola-carrying bats may be heroes as well as villains

REUTERS                                                                                  NOV. 2, 014

By Ben Hirschler

LONDON - Bats are living up to their frightening reputation in the world's worst Ebola outbreak as prime suspects for spreading the deadly virus to humans, but scientists believe they may also shed valuable light on fighting infection.

Fruit bats are seen for sale at a food market in Brazzavile, Republic of Congo, in this file photograph dated December 15, 2005. REUTERS/Jiro Ose/Files

Bats can carry more than 100 different viruses, including Ebola, rabies and severe acute respiratory syndrome (SARS), without becoming sick themselves.

While that makes them a fearsome reservoir of disease, especially in the forests of Africa where they migrate vast distances, it also opens the intriguing possibility that scientists might learn their trick in keeping killers like Ebola at bay.

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What We Don’t Know About Ebola

Overview of what still needs to be learned about the Ebola virus

Research studies have suggested at least three potential paths through which the Ebola virus can invade tissues. Credit Photograph by the C.D.C. via Getty Images

THE NEW YORKER                                      Nov. 1, 2014

By

...there are still serious gaps in what we know about the biology of Ebola, and that ignorance inhibits us from preventing future outbreaks and reducing death rates that still exceed seventy per cent. We don’t know enough about the biology of Ebola to bring the outbreak under full control, or to neutralize the virus once the outbreak is contained. Between on-the-ground efforts and advances in science, we need a balanced approach.

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WHO Updates Guidelines on Ebola Protective Gear

A U.S. doctor in a protective suit in Liberia adjust that of a colleague before entering an Ebola treatment unit in Monrovia in this photo released Sept. 16, 2014.

These updated guidelines aim to clarify and standardize safe and effective PPE options to protect health care workers and patients, as well as provide information for procurement of PPE stock in the current Ebola outbreak. The guidelines are based on a review of evidence of PPE use during care of suspected and confirmed Ebola virus disease patients.

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http://www.who.int/mediacentre/news/releases/2014/ebola-ppe-guidelines/en/

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Africans Worst Responders in Ebola Crisis

ASSOCIATED PRESS                         Oct. 31, 2014
By MICHELLE FAUL
JOHANNESBURG-With few exceptions, African governments and institutions are offering only marginal support as the continent faces its most deadly threat in years, once again depending on the international community to save them.

Ebola "caught us by surprise," the chairwoman of the 53-nation African Union, Nkosazana Dlamini-Zuma, said this week at a meeting with the U.N. secretary-general and the World Bank president in Ethiopia.

"With the wisdom of hindsight, our responses at all levels - continental, global and national - were slow, and often knee-jerk reactions that did not always help," she said.

She is a medical doctor from South Africa, where mining magnate Patrice Motsepe Tuesday announced he has donated $1 million to the fight against Ebola in Guinea, where the outbreak started.

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http://abcnews.go.com/Health/wireStory/africans-worst-responders-ebola-crisis-26596929

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Assessing the Science of Ebola Transmission

THREE ARTICLES DESCRIBING DETAILS OF THE EBOLA VIRUS AND OTHER VIRUSES.
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Advances in microscopy have allowed scientists like Sriram Subramaniam and colleagues at the National Cancer Institute to look at the workings of tiny viruses. In this case, microscopy was used to illustrate the complex process in which human cells infected with HIV-1, green and blue, are linked to uninfected cells. Credit Illustration by Donald Bliss/N.I.H, from The Journal of Virology/American Society for Microbiology

The research on how the virus spreads is not as ambiguous as some have made it seem

THE ATLANTIC                                                                                                          Oct. 28, 2014

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Low HIV and Aids rates saw west Africa ‘miss out on health investment'

THE GUARDIAN                                                                                Oct. 28, 2014
By Sarah Boseley

West Africa, now in the throes of a calamitous Ebola epidemic, missed out on significant health investment over the past decade or more because it had low rates of HIV, a detailed survey of the changing health of Africa and Asia reveals.

The US ambassador to the UN, Samantha Power (centre), visits an ebola emergency response centre in Freetown, Sierra Leone. Healthcare in west Africa now has the world’s attention. Photograph: Reuters

A major project called Indepth, which has looked at the causes of death of more than 110,000 people in 13 countries shows that health improved generally in those given substantial international aid to try to turn around the HIV and Aids epidemic. But west Africa, with severe poverty and low healthcare standards but relatively little HIV, did not benefit.

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